The recently updated American Heartworm Society (AHS) canine heartworm guidelines emphasize the advantages of the protocol over the non-arsenical treatment protocols that have been studied in the U.S. and Europe. While these protocols are needed for dogs that aren’t candidates for melarsomine treatment, the hope is that most heartworm-positive dogs can undergo the AHS treatment regimen, which is designed to eliminate the highest percentage of adult worms while minimizing treatment complications.